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Volume 2, Issue 2, Pages 71-75 (June 2004)


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The WHI and the brain: what have we learned?

Stanley Birge, M.D.aCorresponding Author Informationemail address

Abstract 

The Women's Health Initiative (WHI) cast a dark shadow on HT therapy. However, in the opinion of Dr. Birge, there is an important bright side that has been overlooked—the role of HT on cognitive function. To find out more about the WHI and the brain, read on.

The Editors

a Older Adult Health Center, Division of Geriatrics and Gerontology, Washington University School of Medicine, USA

Corresponding Author InformationStanley Birge, M.D., Associate Professor, Department of Medicine, Director, Older Adult Health Center, Washington University School of Medicine, Division of Geriatrics and Gerontology, 4488 Forest Park Avenue, Health Key Building, Suite 201, St. Louis, MO, USA 63108

 Women with higher levels of estrogen or lower rates of bone loss perform better on measures of cognitive function and are less likely to develop Alzheimer's disease

Analysis of a woman's lifetime risk of disease suggests that the benefits of initiating HT and continuing for 10 years outweigh the risks

Clinical trial data of WHIMS cannot be extrapolated to women initiating HT at the time of menopause

PII: S1546-2501(04)00115-X

doi:10.1016/j.sram.2004.05.001


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